Electrophilic reagent examples
Electrophile. The electrophiles are attacked by the most electronpopulated part of one nucleophile. The electrophiles frequently seen in the organic syntheses are cations such as H and NO, polarized neutral molecules such as HCl, alkyl halides, acyl halides, and carbonyl compounds, polarizable neutral molecules such as Cl2 and Br2,Organometallic Substrates. Aryl and heteroaryl organometallic reagents undergo many of the same transformations as their aliphatic counterparts. Formation of amines, hydrazines, and azides is possible through the use of various electrophilic aminating reagents. An electrophilic reagent examples
Nucleophilic and Electrophilic Reagents. Examples of nucleophilic substitution include hydrolysis, with the nucleophiles OH and H 2 O; alcoholysis, in which the nucleophiles are RO and ROH; acidolysis, with the nucleophiles RCOO; and RCOOH; amination, involving such nucleophiles as NH 2, NH 3, and RNH2; and cyanation, with the nucleophile CN.
As the aromaticity of benzene is not disturbed in the reaction, these reactions are highly spontaneous in nature. Basic examples of electrophilic substitution reaction of benzene are nitration, sulfonation, halogenation, Friedel Crafts alkylation and acylation, etc. The mechanism for electrophilic How can the answer be improved?electrophilic reagent examples The action of these electrophilic reagents on has also been reported (77BSF676). However, other electrophilic substitution reactions of 2, such as sulfonation, iodination and FriedelCrafts acylation, have been unsuccessful (71T487).